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Hacker Trends › “semaglutide” trend

How “semaglutide” trended on Hacker News

“Semaglutide” was mentioned 1,054 times on Hacker News between 2020 and 2026, peaking in Oct 2024 with 63 that month.

Every month from 2007 to 2026, counting how often “semaglutide” appears in Hacker News stories and comments. Each point is a live date-histogram over ~45M items, computed with Upstash Redis Search.

Total mentions
1,054
Peak month
Oct 2024 (63)
First seen
2020
2008201120142017202020232026
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What the chart shows

Semaglutide — the compound behind Ozempic and Wegovy — first appears in 2020 and is a lower-volume term at 1,054 lifetime mentions. The curve peaks in October 2024 with 63 mentions, a modest spike in a steady upward trend.

Discussion is clinical and practical: reduced alcohol addiction associations, an argument that the drug “changed the world,” patent-expiry timelines in several countries, and Ask HN threads on weight-loss experience. Interest persisted into 2026.

Top Hacker News stories about “semaglutide”

  1. 1.Wegovy and Ozempic (semaglutide) associated with reduction in alcohol addiction 76 points · 162 comments · 2024 · discuss on HN
  2. 2.Semaglutide Has Changed the World 50 points · 16 comments · 2022 · discuss on HN
  3. 3.Ask HN: Anyone try semaglutide / Wegovy for weight loss? 49 points · 65 comments · 2022 · discuss on HN
  4. 4.Semaglutide loses patent protection in '26 in India, Canada, Brazil and Turkey 41 points · 28 comments · 2025 · discuss on HN
  5. 5.Show HN: I Researched Semaglutide (Ozempic) Clinics in the United States 10 points · 10 comments · 2024 · discuss on HN
  6. 6.GLP-1 Second-Order Effects 7 points · 2 comments · 2026 · discuss on HN
  7. 7.Once-Weekly Semaglutide in Adults with Overweight or Obesity 5 points · 1 comments · 2021 · discuss on HN
  8. 8.San Francisco Hims disrupts Ozempic with $200/month generic semaglutide 5 points · 3 comments · 2024 · discuss on HN
  9. 9.Antipsychotic-treated patients with schizophrenia see benefits from semaglutide 5 points · 1 comments · 2025 · discuss on HN
  10. 10.Semaglutide and Dementia: A 1.7M Patient Study in Off-Label Use 5 points · 0 comments · 2025 · discuss on HN
  11. 11.Once-Weekly Semaglutide in Adults with Overweight or Obesity 4 points · 0 comments · 2021 · discuss on HN
  12. 12.Semaglutide trial shows 15% weight loss after a year in 1,961 adults 4 points · 0 comments · 2021 · discuss on HN

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