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Hacker Trends › “glp-1” trend

How “glp-1” trended on Hacker News

“Glp-1” was mentioned 2,365 times on Hacker News between 2009 and 2026, peaking in Jul 2025 with 185 that month.

Every month from 2007 to 2026, counting how often “glp-1” appears in Hacker News stories and comments. Each point is a live date-histogram over ~45M items, computed with Upstash Redis Search.

Total mentions
2,365
Peak month
Jul 2025 (185)
First seen
2009
2008201120142017202020232026
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What the chart shows

GLP-1 shows up as early as 2009 in a clinical context, but mention volume rose with the weight-loss drug wave. The curve peaks in July 2025 with 185 mentions, and the lifetime total is 2,365 mentions — a steady recent climb rather than a single spike.

The conversation is broad and medical: threads on GLP-1 drugs as an economic disruptor, effects on life insurance, and emerging research links to substance-use disorders, colon-cancer survival, and migraine frequency. Interest remained active heading into 2026.

Top Hacker News stories about “glp-1”

  1. 1.GLP-1s are breaking life insurance 441 points · 620 comments · 2025 · discuss on HN
  2. 2.GLP-1 drugs: An economic disruptor? (2024) 385 points · 531 comments · 2025 · discuss on HN
  3. 3.Ask HN: How to raise funds for rare disease research? 260 points · 205 comments · 2022 · discuss on HN
  4. 4.GLP-1 therapeutics: Their emerging role in alcohol and substance use disorders 254 points · 198 comments · 2025 · discuss on HN
  5. 5.GLP-1 drugs linked to lower death rates in colon cancer patients 241 points · 203 comments · 2025 · discuss on HN
  6. 6.From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency 156 points · 113 comments · 2025 · discuss on HN
  7. 7.Drug Development Failure: how GLP-1 development was abandoned in 1990 152 points · 166 comments · 2024 · discuss on HN
  8. 8.GLP-1 for Everything 150 points · 233 comments · 2024 · discuss on HN
  9. 9.GLP-1 therapy increases visceral adipose tissue metabolic activity 105 points · 118 comments · 2024 · discuss on HN
  10. 10.There may not be a safe off-ramp for some taking GLP-1 drugs, study suggests 74 points · 103 comments · 2025 · discuss on HN
  11. 11.GLP-1s are among the most important drug breakthroughs 58 points · 147 comments · 2024 · discuss on HN
  12. 12.Drinking alcohol reduces the body's natural GLP-1 activity by 34% 51 points · 22 comments · 2024 · discuss on HN

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